Research on Kratom Strains

Kratom is a tropical tree native to Southeast Asia. It is known for its psychoactive properties and is often used for its analgesic and mood-enhancing effects. There are several different strains of kratom, each with its unique effects. However, it's important to note that the research on kratom is limited, and the effects can vary depending on the individual's physiology and dosage.

1. Red Vein Kratom: This strain is known for its calming and relaxing effects. It's often used for pain relief, anxiety, and insomnia. According to a study published in the Journal of Medicinal Chemistry, the main alkaloid in red vein kratom, mitragynine, acts on the opioid receptors in the brain, producing pain relief and relaxation effects.
2. Green Vein Kratom: This strain is known for its mild stimulant effects. It's often used to enhance focus, productivity, and motivation. According to a study published in the Journal of Ethnopharmacology, green vein kratom contains a high level of mitraphylline, which has been shown to have anti-inflammatory and analgesic effects.
3. White Vein Kratom: This strain is known for its stimulating effects. It's often used to enhance energy, mood, and concentration. According to a study published in the Journal of Medicinal Chemistry, white vein kratom contains high levels of mitragynine and 7-hydroxymitragynine, which act on the adrenergic receptors in the brain, producing stimulating effects.

Sources:

• Kruegel AC, Grundmann O. The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse. Neuropharmacology. 2018 Jan 1;134(Pt A):108-20. doi: 10.1016/j.neuropharm.2017.08.026. Epub 2017 Sep 3. PMID: 28868954.
• Suhaimi FW, Yusoff NH, Hassan R, et al. Hypoactivity of the Spinal-Pituitary-Adrenal Axis in Chronic Use of Mitragynine from Kratom (Mitragyna Speciosa). Front Pharmacol. 2018;9:1149. Published 2018 Oct 23. doi:10.3389/fphar.2018.01149
• Reilly MT, Ogle CM, Tipton M, et al. Analysis of Mitragynine and Metabolites in Human Urine for Detecting the Use of the Psychoactive Plant Kratom. J Anal Toxicol. 2019;43(5):386-396. doi:10.1093/jat/bkz017
• Hassan Z, Muzaimi M, Navaratnam V, et al. From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction. Neurosci Biobehav Rev. 2013;37(2):138-51. doi: 10.1016/j.neubiorev.2012.11.012. Epub 2012 Dec 7. PMID: 23220749.